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Migraine drugs may also help with weight loss

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Researchers at UT Southwestern revealed in a new study that Triptans, a common migraine drug, can also help those struggling to lose weight.

The study focused on examining obesity in mice and found that a daily dose of Triptan led them to lose weight in approximately a month.

“We’ve shown that there is real potential to repurpose these drugs, which are already known to be safe, for appetite suppression and weight loss,” said lead study author, Chen Liu PhD.

Beforehand, scientists already knew that serotonin, a chemical messenger in the brain and body, plays an important role in determining one’s appetite. But there are 15 different serotonin receptors that trigger a behavioural change in cells.

This new experiment revealed that Triptans target the serotonin 1B receptor, which hadn’t been studied closely before in analyzing appetite and weight loss.

To conduct the study, researchers fed obese mice a high-fat diet for seven weeks. After 24 days, mice given Truptan lost 3.6 per cent of their body weight while mice that weren’t given the drug gained 5.1 per cent.

“We found that these drugs, and one in particular, can lower body weight and improve glucose metabolism in less than a month, which is pretty impressive,” said Dr Liu.

The study was published in the Journal of Experimental Medicine.

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ANF Operation: Police Apprehend 1883 Dealers and Seize 1049 Mt of Drugs

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The Pakistani government along with the military leadership have initiated a strict campaign against drug dealers in an attempt to tackle drug addiction.

1,883 drug dealers have been detained and 1,049.78 metric tonnes of drugs have been recovered by authorities since the start of operations in September 2023.

There were 3.66 metric tonnes of heroin and 47.84 metric tonnes of hashish found among the narcotics confiscated. In addition, 985.20 metric tonnes of various drugs, 9.25 metric tonnes of opium, and 3.83 metric tonnes of meth were seized.

The following drug loads were apprehended by security authorities between September 1 and September 10: 278 kg in Balochistan, 23.63 kg in Khyber Pakhtunkhwa, 11.14 kg in Gilgit-Baltistan, 226.31 kg in Punjab, and 27.73 kg in Sindh.

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Musadik Malik: 10 Fertiliser Plants Receiving Gas at Different Prices

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According to federal minister of petroleum Musadiq Malik, there are ten fertiliser factories in the nation, and the cost of petrol varies depending on the plant.
In response to a query in the Senate, the Minister of Petroleum stated that indigenous gas supplies to these plants do not involve any subsidies.
Additionally, the Minister stated that two of the nation’s plants run on subsidised LNG, with the difference being cross-subsidized to recover costs from RLNG users.
The suspension of Pakistan Tehreek-e-Insaf member Falak Naz Chitrali from the parliament was demanded by members of the Balochistan Awami Party and the treasury benches later in the Senate session.
It was asked by both parties that the PTI Senator be suspended for a full two working days.
Senate Deputy Chairman Seydaal Khan Nasir adjourned the meeting, setting a new date for Saturday.

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Interior Minister Applauds CTD For Conducting Operation Against Terrorists: Terror Bid Foiled In DG Khan

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Interior Minister Mohsin Naqvi praised Punjab’s Counter Terrorism Department for foiling a terrorist plot and taking down Fitna-ul-Khawarij militants in Dera Ghazi Khan.

Fitna-ul-Khawarij’s two terrorists were sent to hell, according to a statement made by the Interior Minister of CTD Punjab.

CTD Punjab, according to Mohsin Naqvi, is spearheading the fight against terrorism.

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