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Genetic mapping reveals how cancer grows

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Scientists all over the world have been trying to understand cancer, which is one of the deadliest diseases in the world, for many years.

Researchers have been trying to figure out where cancer comes from and what early treatments can help counter this illness.

Now, researchers have created a map of the prostrate which shows healthy areas and those that contain cancerous cells.

Experts from the Karolinska Institutet, Solna, Sweden, the University of Oxford, and KTH Royal Institute of Technology, Science for Life Laboratory discovered that prostrate tumours have an unknown range of genetic variation.

The team saw what genetic changes take place in the tissue using spatial transcriptomics. Their work can play an immense role in improving early cancer diagnosis.

The study published in the journal Nature said that this technique was better because the older ones take samples from cancerous areas and study the DNA of cells with tumours only. Researchers said that prostrate cancer and others like it are three-dimensional and any one sample should hint toward a tumour.

The lead of the study, Alastair Lamb, said that they were “fairly sure” cancer started with genetic mutations. Lamb said that this amount of clarity was never there before.

To the surprise of the scientists, genetic characteristics of cancer were seen in healthy tissues too. 

In their vast study, researchers scrutinised 150,000 regions in two breast cancers, a lymph node, some skin, some brain tissue, and three prostrates to develop an algorithm that could track cells with similar genetic characteristics.

“Mapping thousands of tissue regions in a single experiment is an unprecedented approach to deconvolute the heterogeneity of tumours and their microenvironment,” said Professor Joakim Lundeberg of KTH Royal Institute of Technology.

He said that high-resolution views can change the way we look at the cancer ecosystem. 

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Bitcoin rises beyond $64,000 as new records are set.

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On Monday, Bitcoin reached a two-year high and broke $64,000 as a surge of capital brought it dangerously close to record highs.

It reached its best level since late 2021 at $64,285 early in the Asian day, and it closed the session 2% higher at $63,850. The highest point for bitcoin was $68,999.99, reached in November 2021.

This year, the largest cryptocurrency by market value has increased by 50%, with the majority of the gain occurring in the last few weeks due to a spike in trading volume for U.S.-listed bitcoin funds.

Earlier this year, US authorities legalised spot bitcoin exchange-traded funds.

Their introduction provided access for new major investors and has sparked renewed energy and enthusiasm similar to the surge to all-time highs in 2021.

As investors gain confidence, the flows don’t seem to be stopping, according to Markus Thielen, head of research at Singapore-based cryptocurrency analytics firm 10x Research.

Rival, smaller ether, has benefited from conjecture that exchange-traded funds may soon be the source of inflows for it as well. Although it’s up 50% so far this year, Monday’s price of $3,490 was barely below two-year highs set last week.

Alongside the rally, stock index records have tumbled on the Nikkei (.N225) in Japan, opened a new tab on the S&P 500 (.SPX), opened a new tab on the tech-heavy Nasdaq (.IXIC), opened a new tab on volatility gauges in equities (.VIX), opened a new tab on foreign exchange (.DBCVIX), and opened a new tab on the S&P 500 (.SPX).

“As long as bitcoin continues to be a high-volatility tech proxy and liquidity thermometer, cryptocurrency will do well in a world where the Nasdaq is setting new all-time highs,” said Brent Donnelly, president and trader at Spectra Markets.

“The market is back to how it was in 2021, when everything is rising and people are having a good time.”

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WhatsApp adds a calendar function to make message retrieval simple.

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The “search by date” tool is an inventive innovation that makes it simple for users to access their favourite previous chats.

Users of Android and iPhone may now search for messages or media on a given day by using the app’s calendar interface, which is a new feature of the update. The laborious process of manually reading through chat history is eliminated by this function, which is especially helpful for regular users who have large message archives.

The announcement was also announced by Meta CEO Mark Zuckerberg on his WhatsApp channel, highlighting the company’s dedication to improving user accessibility and ease.

When users click on the calendar icon and choose a desired date, WhatsApp takes them directly to the messages that were sent and received on that specific day. This makes searching easier, which is especially helpful for those looking for certain details or memories that are hidden in their conversation history.

The addition of the calendar function to WhatsApp’s recent version rollout brings more formatting options for text, including strikethrough, bold, italic, and monospace. Additionally, the platform has given security improvements first priority, guaranteeing a secure environment for its large user base.

Nevertheless, in the middle of these developments, Android users of WhatsApp should be aware of a recent modification pertaining to conversation backups. Google Drive backups of conversations are no longer available for free since they now count against the user’s storage allotment.

To utilise this new feature, users can simply access WhatsApp, select a chat, tap on the name of the person or group, and choose the “Search” option. The calendar interface will then facilitate seamless navigation to messages from the selected date.

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VPNs, X, and Slow Internet Services Are Still Blocked in Pakistan

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Users are reporting poor performance on numerous social media sites due to widespread slowdowns in internet access. Furthermore, X (previously Twitter) has been inaccessible for the past six days, despite the Sindh High Court’s directive to allow access. In the meantime, Pakistan is blocking VPN services.

X Remains Unblockable

On February 17, 2024, the Pakistani government first prohibited access to X when it was discovered that Rawalpindi’s Commissioner had rigged election results. The block is still in effect, even though there has been no official announcement or explanation for it. Despite the Supreme Court’s decision to lift the prohibition, the administration has not yet disclosed any plans for reinstatement. Furthermore, officials are giving media outlets conflicting information about the limitations.

Blocked VPN Services

Virtual private network (VPN) services are being widely blocked nationwide, which exacerbates the problem. Apart from limiting accessibility to X, the government has initiated the banning of prominent VPN providers, impeding users’ capacity to establish connections with any server.

sluggish internet access

There is a noticeable slowdown in internet speeds and a decline in performance across Pakistan. The problem hasn’t been acknowledged by the Pakistan Telecommunications Authority (PTA), nevertheless. Even though internet service providers (ISPs) insist there aren’t any outages, consumers on social media sites are nonetheless complaining about poor access.

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