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Monkeypox symptoms, diagnosis, treatments and vaccines

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  • More than 16,000 confirmed cases have been recorded in 75 countries so far this year, says WHO.
  • First symptoms can include a fever, headaches, sharp muscle pains, fatigue, a rash, and swollen and painful lymph nodes.
  • Monkeypox has long been endemic in Central and Western Africa.

PARIS: The World Health Organisation declared monkeypox a global health emergency at the weekend, as calls grow for swift action to stop the spread of the virus.

More than 16,000 confirmed cases have been recorded in 75 countries so far this year, the WHO said on Monday.

Here is an overview of the symptoms, diagnosis, treatments and vaccines.

Symptoms 

The first symptoms can include a fever, headaches, sharp muscle pains, fatigue, a rash, as well as swollen and painful lymph nodes.

Around one to three days after the appearance of a fever, a rash can turn into painful, fluid-filled skin lesions.

After a few days or weeks, the lesions or sores turn into scabs, before falling off.

Monkeypox has long been endemic in Central and Western Africa. In countries elsewhere that have recorded cases since May, the lesions have been more common around the genitals and anus, as well as on the mouth.

On Monday, the UK Health Security Agency expanded its list of symptoms to include just one or two genital or anal lesions, as well as rectal pain or bleeding.

Symptoms have varied between patients, however. They usually last between two to four weeks, and the virus is contagious until the rash has fully healed.

Diagnosis 

Most of the recent global cases have been in men who have been intimate with men and have recently been with a new partner, according to the WHO.

A study published in the New England Journal of Medicine last week found that 95% of cases were transmitted through sexual activity.

Diagnosing the virus can be difficult due to its inconsistent symptoms, which can resemble sexually transmitted infections, several health authorities have warned.

Europe has been the epicentre of the outbreak, with many cases among younger men living in cities, according to the WHO.

Confirming a case of monkeypox may require a PCR test or a sample or biopsy of a skin lesion.

Those with potential cases must isolate while waiting for test results. Once the virus is confirmed, isolation is recommended for three weeks.

Monkeypox has been detected in semen but is not considered a sexually transmitted disease, instead spreading through close physical contact. The European Centre for Disease Prevention (ECDC) recommends using a condom for 12 weeks after recovery.

Treatment 

The disease usually heals by itself after two to three weeks, sometimes taking a month.

In many cases, the only treatment needed is to address the symptoms, such as clearing up a fever or soothing the itching.

Sometimes the lesions can become extremely painful, however, requiring serious painkillers or even hospital treatment.

The most severe cases have been seen in children, pregnant women and people with comprised immune systems.

No deaths have been reported so far in Europe or the United States.

People with monkeypox are advised not to scratch the lesions, as this could spread the virus or leave a scar, and to cover them to avoid the temptation.

The European Medicines Agency has approved a smallpox medication, Tecovirimat, for monkeypox treatment.

Vaccines 

A smallpox vaccine from Danish drug maker Bavarian Nordic, marketed under the name Jynneos in the United States and Imvanex in Europe, has also been found to protect against monkeypox.

The European Commission approved its use for monkeypox on Monday.

It can also have a “significant protective effect” if administered within four days of exposure to a monkeypox case, according to the ECDC.

Countries such as Britain, Canada, France and the United States have started offering vaccination to those most at risk of the virus.

The vaccine is given in two doses, at least 28 days apart. But for people vaccinated against smallpox as children, one dose is enough. For people with comprised immune systems, a third dose is recommended.

As the vaccines do not provide immediate or total protection, health authorities advise caution after receiving an injection.

The United States also has many doses of the older generation ACAM2000 smallpox vaccine, but it is not recommended for everyone because of significant side effects.

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The IHC upholds Bushra Bibi’s request to be transferred from Bani Gala to Adiala Jail.

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Bushra Bibi’s request to be transferred from Bani Gala to Adiala Jail was granted by the Islamabad High Court (IHC) on Thursday.

The former first lady Bushra Bibi’s application to be transferred from Bani Gala sub-jail to Adiala was heard today.

Details reveal that the Islamabad High Court heard a motion to restore the denied petition about the relocation of Bushra Bibi, the wife of PTI founder, from sub-jail Bani Gala to Adiala.

The application for the reinstatement of appeal was heard by Justice Miagul Hassan Aurangzeb. When state attorney Abdul Rehman entered the courtroom on behalf of the state, Usman Riaz Gill represented the former first lady.

State counsel did not object to the appeal being restored during court proceedings. At the following hearing, the court asked for assistance in determining what conditions must be met for a location to be designated as a sub-jail.

The court also mandated that Bushra Bibi’s medical examination be scheduled. The court subsequently delayed the hearing and gave instructions to fix the appeal for April 22.

Recall that the attorneys for former first lady Bushra Bibi, Barrister Salman Safdar, Usman Riaz Gill, and Khalid Yusuf Chaudhary, had filed an application to restore the dismissed appeal a day ago, but the Islamabad High Court had denied their request to pursue the case.

The petition contended that the traffic gridlock at the Sarina Chowk checkpoint was the reason for the delay in getting to the court.

The attorneys did not purposefully take their time getting to court. They warned that the petitioner would suffer irreversible loss if the petition was not resurrected.

IHC Justice Miangul Hassan Aurangzeb has voiced his displeasure at the absence of attorneys from the court.

According to Judge Aurangzeb, the former first lady would have been imprisoned if Bushra Bibi’s attorneys had prevailed in this case. The attorneys themselves were opposed to Bushra Bibi’s incarceration.

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oath-taking ceremony for the Balochistan cabinet postponed

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The Balochistan cabinet’s oath-taking ceremony, which was supposed to take place at the Governor’s House today (Thursday), has been rescheduled.
The Governor’s House spokeswoman announced that the Balochistan cabinet’s swearing-in event has been postponed. Nevertheless, there was no explanation provided for the ceremony’s postponement.

It is important to note that the 14-member Balochistan cabinet, which consists of two members from the Balochistan Awami Party (BAP) and six ministers from the Pakistan Muslim League-Nawaz (PML-N) was set to take the oath of office today, Thursday.

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PMD forecasts rain throughout the majority of the nation.

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During the next 24 hours (Thursday–Friday), the Pakistan Meteorological Department (PMD) has predicted rain, windstorms, thunderstorms, and a few torrential downpours or hailstorms throughout the majority of Khyber Pakhtunkhwa, Gilgit-Baltistan, Kashmir, Islamabad, Punjab, and Balochistan.

In several areas of Sindh, a rain-windstorm/thunderstorm is anticipated. Much of Balochistan is being hit by a powerful westerly wave trough, which is expected to spread to the top regions by April 18.

Prolonged downpours have the potential to cause flash flooding in Balochistani local streams and drains, particularly in Gwadar, Jiwani, Pasni, Ormara, Kech, Awaran, Kharan, Panjgur, Washuk, Noshki, Lasbela, Khuzdar, and Kalat.

On April 18–20, heavy rains could cause flash floods in tributaries of the Kabul River as well as in Dir, Swat, Chitral, Kohistan, Manshera, Gilgit–Baltistan, Kashmir, and other areas.

Lower Khyber Pakhtunkhwa, Murree, Galiyat, Kashmir, and Gilgit-Baltistan are among the regions where landslides may occur.

At this time, standing crops, power poles, cars, solar panels, and other objects may sustain damage from wind, hail, and lightning, according to meteorologists.

Upper Sindh and Balochistan saw rain, wind, and thunderstorms in the past 24 hours. During the era, there were also significant rainfalls in South Balochistan. Wednesday’s highs of 42 degrees Celsius in Mithi kept it as the country’s hottest spot.

Officials reported that lightning-related storm-related occurrences claimed the lives of at least 65 people in Pakistan, where the rate of precipitation in April has so far been roughly twice that of previous years. Floods and house collapses were caused by heavy downpours that occurred between Friday and Monday. Lightning claimed 28 lives.

32 people, including 15 children, have killed and over 1,300 homes have been damaged in northwest Khyber Pakhtunkhwa, which has suffered the greatest victim count.

The meteorological experts report that there is little probability of rain, despite the fact that drizzle fell in numerous areas of Karachi.

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